Performance Assessment of Binary Output Examinations in Medical Laboratories
Content
The determination of clinical sensitivity and specificity of tests for binary disease detection is critical to ensure these tests are sufficiently reliable.
Clinical sensitivity (SP), also known as the True Positive Rate, describes the probability of correctly detecting a disease case. Clinical Specificity (SS), also known as the True Negative Rate, expresses the ability to correctly identify the absence of a disease.
Since the accuracy of the determined SP and SS depends on the number of tested known disease cases, it is important to determine the confidence intervals for estimates of the performance parameter. These confidence intervals are subsequently used to decide if the actual performance and its quantification method are adequate.
This leaflet provides an overview of what is involved in these crucial assessments.
Availability
The second edition is currently available in English.
- Download the leaflet in English [691 kb] (2025-05-30)*
* Dates are the date of addition to this website
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- Last Updated: Friday, 30 May 2025 23:04