Eurachem Working Groups

Method Validation Working Group

The Eurachem Method Validation Working Group (MVWG) aims to function as a centre of expertise in the field by assembling and promoting best practice in Method Validation.

Terms of Reference

  1. The EURACHEM Method Validation Working Group has been established and will operate in accordance with the Constitution agreed in the EURACHEM Memorandum of Understanding, and is as such working:
  2. To provide guidance on method validation. This guidance, "Fitness for Purpose of Analytical Methods", will be applicable to all chemical analytical laboratories and meet the requirements for accreditation
  3. To organize - and contribute to - international seminars and workshops on issues related to Method Validation within analytical chemistry
  4. To collaborate and provide input on Method Validation into other Eurachem working groups
  5. To follow and discuss new developments within analytical chemistry, which may require new approaches regarding Method Validation
  6. To contribute to the "Reading List" with relevant references on Method Validation in analytical chemistry.

Activities

 Past

  • MVWG was co-arranger of an international workshop, “Validation / Traceability / Measurement Uncertainty. Challenges for the 21st Century’s analysts”, in Berlin in May 2012 (see under "Completed Events")
  • The MVWG issued a revised edition of the Eurachem Fitness for Purpose guide in 2014 and is currently considering supplementary guidance on individual aspects of method validation.
  • A scientific committee based in the MVWG planned a 2-day Workshop, "Method Validation - Current Practices and Future Challenges" in Ghent, Belgium, May 2016
  • Contributing with a 3 hours workshop "Are MS-based methods fit for purpose?" at the XXII International Mass Spectrometry Conference in Florence, Italy, August 26 - 31 2018
  • Contributing to the scientific program of the Eurachem Workshop "Validation of targeted and non-targeted methods of analysis" in Tartu, Estonia, May 20 - 21 2019
  • Contributing with with a 2 hour workshop at the AOAC Europe – NMKL – NordVal International symposium, "SPEEDING TOWARDS –OMICS…" in Oslo, Norway, June 3-4, 2019

Current

  • The MVWG is normally meeting twice a year. Since 2020 these meetings have been online meetings (supplemented by various task groups having occassional online chats on specific topics)

Members of MVWG assempled face-to-face
for the last time before Covid
(Rome, February 2020)

  • The MVWG is currently considering and working on supplementary guidance on individual aspects of method validation, either to be included in a coming version of the "Fitness for Purpose" guide as annexes or to be issued as supplements to the main guide.
    So far the following supplements have been issued:
    "Planning and reporting method validation studies"
    "Blanks in Method Validation"
    ...and more are in the pipeline
  • The MVWG ihave started the work on review/revision of the guide (3rd edition due around 2020-21). 
  • The MVWG is working on illustrative examples (validation protocols) on application of the principles recommended in the "Fitness for Purpose" guide.
  • A Task Group on Validation of Non-Targeted Methods has been established. Arranging a series of ½-day webinars on the subject in cooperation with AOAC-E.
  • A Joint Task Group (JTG) has been set up in cooperation with the Sampling Uncertainty WG and with inputs from Eurolab and NMKL, to prepare Supplementary Guidance on the Validation of Measurement Procedures that Include Sampling. Initial discussions within the JTG have focused on the balance between the quantitative and descriptive approach, and also between the integrated and isolated approach. A Discussion Forum, joint with Eurolab, was held online on 4th May 2022 to engage with the wider user community and attracted 450 participants.

Comment on our guidance

The MVWG will appreciate comments on the present version of the "Fitness for Purpose" guide (Ed. 2, 2014).
This can be done by using the Feedback form on the Eurachem Fitness for Purpose guide (opens on separate site)

Contact the Working Group

The working group may be contacted via the working group Secretary using the Website contact form.
If interested in membership of the working group, the document "Method Validation Working Group – Roles & Responsibilities" should be requested from the secretary. 

Members

  • Isabelle Vercruysse (Belgium)
  • Edouard Salingros (Belgium)
  • Lorens Sibbesen (Denmark; Chair)
  • Piotr Robouch (JRC/EU) (C)
  • Pieter Dehouck (JRC/EU)
  • Abdelkader Boubetra (France)
  • Barbara Pohl (Germany) (C)
  • Stephan Walch (Germany)
  • Helen Gika (Greece)
  • Marios Kostakis (Greece)
  • Éidín Christie (Ireland)
  • Helen Cantwell (Ireland; Vice Chair & Secretary)
  • John Clancy (Ireland)
  • Emanuela Gregori (Italy)
  • Marina Patriarca (Italy)
  • Elin Lovise Folven Gjengedal (Norway) (C)
  • Ewa Bulska (Poland) (C)
  • Pedro Pablo Morillas Bravo (Spain)
  • Francisco Raposo (Spain)
  • Elvar Theodorsson (Sweden) (C)
  • Ulf Örnemark (Sweden) (C)
  • Ernst Halder (Switserland)
  • Fatma Akcadag (Turkey)
  • Burcu Binici (Turkey)
  • Aysun Yilmaz (Turkey)
  • Perihan Yolci Ömeroglu (Turkey)
  • Vicki Barwick (UK)
  • Steve Ellison (UK) (C)
    (C): Corresponding member