Eurachem Working Groups

Method Validation Working Group

The Eurachem Method Validation Working Group (MVWG) aims to function as a centre of expertise in the field by assembling and promoting best practice in Method Validation.

Terms of Reference

The Eurachem Method Validation Working Group has been established and will operate in accordance with the Constitution agreed in the Eurachem Memorandum of Understanding. It will function as a centre of expertise by identifying and developing best practices on how to ensure that analytical methods are fit for purpose. The MVWG is working:

  1. To provide guidance on method validation. This guidance will be applicable to all analytical laboratories and meet the requirements for accreditation;
  2. To organize - and contribute to - international seminars and workshops on issues related to method validation within analytical measurement;
  3. To collaborate and provide input on method validation into other Eurachem working groups, joint task groups and other professional liaison organisations;
  4. To follow and discuss new developments within analytical measurement, which may require new approaches regarding method validation;
  5. To contribute to the "Reading List" with relevant references on method validation in analytical measurement.



  • MVWG was co-arranger of an international workshop, “Validation / Traceability / Measurement Uncertainty. Challenges for the 21st Century’s analysts”, in Berlin in May 2012 (see under "Completed Events")
  • The MVWG issued a revised edition of the Eurachem Fitness for Purpose guide in 2014 and is currently considering supplementary guidance on individual aspects of method validation.
  • A scientific committee based in the MVWG planned a 2-day Workshop, "Method Validation - Current Practices and Future Challenges" in Ghent, Belgium, May 2016
  • Contributing with a 3 hours workshop "Are MS-based methods fit for purpose?" at the XXII International Mass Spectrometry Conference in Florence, Italy, August 26 - 31 2018
  • Contributing to the scientific program of the Eurachem Workshop "Validation of targeted and non-targeted methods of analysis" in Tartu, Estonia, May 20 - 21 2019
  • Contributing with with a 2 hour workshop at the AOAC Europe – NMKL – NordVal International symposium, "SPEEDING TOWARDS –OMICS…" in Oslo, Norway, June 3-4, 2019


  • The MVWG normally meets twice a year. One of these meetings takes place online while the second is in person. In addition, task groups may have occassional online chats on specific topics.
    MVWG 2020 02

Members of MVWG assempled face-to-face
for the last time before Covid
(Rome, February 2020)

  • The MVWG is currently working on supplementary guidance on individual aspects of method validation, either to be included in a coming version of the "Fitness for Purpose" guide as annexes or to be issued as supplements to the main guide.
    So far the following supplements have been issued:
    "Planning and reporting method validation studies"
    "Blanks in Method Validation"
    ...and more are in the pipeline
  • The MVWG are currently finalising work on revision of the Fitness for Purpose guide (3rd edition due around 2024). 
  • The MVWG is working on preparing a supplement which contains examples which apply the principles recommended in the "Fitness for Purpose" guide.
  • A Task Group on Validation of Non-Targeted Methods has been established. Arranging a series of ½-day webinars on the subject in cooperation with AOAC-E.
  • A Joint Task Group (JTG) has been set up in cooperation with the Sampling Uncertainty WG and with inputs from Eurolab and NMKL, to prepare Supplementary Guidance on the Validation of Measurement Procedures that Include Sampling. Initial discussions within the JTG have focused on the balance between the quantitative and descriptive approach, and also between the integrated and isolated approach. A Discussion Forum, joint with Eurolab, was held online on 4th May 2022 to engage with the wider user community and attracted 450 participants.

Contact the Working Group

The working group may be contacted via the working group Secretary using the Website contact form.
If interested in membership of the working group, the document "Method Validation Working Group – Roles & Responsibilities" should be requested from the secretary. 


  • Isabelle Vercruysse (Belgium)
  • Lorens Sibbesen (Denmark)
  • Piotr Robouch (JRC/EU) (C)
  • Pieter Dehouck (JRC/EU; Vice-Chair/Secretary)
  • Abdelkader Boubetra (France)
  • Nathalie Guigues (France)
  • Barbara Pohl (Germany) (C)
  • Stephan Walch (Germany)
  • Helen Gika (Greece)
  • Marios Kostakis (Greece)
  • Helen Cantwell (Ireland; Chair)
  • John Clancy (Ireland)
  • Karen Moore (Ireland)
  • Emanuela Gregori (Italy)
  • Marina Patriarca (Italy)
  • Elin Lovise Folven Gjengedal (Norway) (C)
  • Ewa Bulska (Poland) (C)
  • Pedro Pablo Morillas Bravo (Spain)
  • Francisco Raposo (Spain)
  • Elvar Theodorsson (Sweden) (C)
  • Ernst Halder (Switserland)
  • Fatma Akcadag (Türkiye)
  • Burcu Binici (Türkiye)
  • Aysun Yilmaz (Türkiye)
  • Perihan Yolci Ömeroglu (Türkiye)
  • Vicki Barwick (UK)
  • Steve Ellison (UK) (C)
    (C): Corresponding member